Author: annawilson

David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and NF Center Director, was one of 48 recipients of the Alexander von Humboldt Award. At the Humboldt Annual Fellows meeting held in Berlin on June 26th, Dr. Angela Merkel, Chancellor of the Federal Republic of Germany delivered the keynote speech, followed by a […]

Kelly Hartigan, an undergraduate student at Washington University, presented her summer research project at the Pediatric Student Research Program (PSRP) Symposium on Friday July 26, 2019. Kelly worked with MSTP student, Michelle Wegscheid, in the laboratory of Dr. David Gutmann. She shared her exciting findings using NF1 patient induced pluripotent stem cells to study human […]

Most children with Neurofibromatosis Type 1 (NF1) have difficulties with learning and/or behavior; however, these problems vary significantly between individuals. While deficits may affect all areas of learning and behavior, other impairments only affect one area. Adaptive functioning measures an individual’s ability to achieve age-appropriate maturity, judgment and reasoning, social sensibility, and personal independence. Adaptive […]

Nicole M. Brossier, MD, PhD, a postdoctoral research fellow in the laboratory of Dr. David Gutmann at Washington University, was recently awarded research fellowship grants from both Hyundai Hope on Wheels and Alex’s Lemonade Stand Foundation to continue her exciting work on the origins of pediatric brain tumors. Dr. Brossier is completing her pediatric hematology/oncology […]

David H. Gutmann, MD, PhD recently finished his four-year term as a member of the Advisory Council for the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH). This national advisory council advises the NINDS on policy and procedures affecting its research programs and provides a second level of […]

Yuan Pan, PhD, was recently awarded the Early Investigator Research Award from the Department of Defense Neurofibromatosis (NF) Research Program. The Early Investigator Research Award was to support NF-focused research and promote career development towards an independent researcher in the NF field. Dr. Pan joined Dr. Gutmann’s laboratory as a postdoctoral research fellow to study […]

David H. Gutmann, MD, PhD, Donald O. Schnuck Family Professor and Vice Chair for Research Affairs for Neurology, was recently honored for twenty five years of service as faculty at Washington University. Upon his arrival in St. Louis in late 1993, he established the Neurofibromatosis (NF) Clinical Program at St. Louis Children’s Hospital to care […]

Monocytes/macrophages are immune system-like cells important for normal brain function. In the healthy brain, resident microglia are the major macrophage cell population; however, in brain tumors, peripheral monocytes/macrophages can infiltrate the brain and participate in brain tumor growth. Distinguishing these two populations is often challenging, owing to a paucity of universally accepted and reliable markers. […]

Elizabeth Wright-Jin, MD, PhD recently joined the research laboratory of NF Center Director, David H. Gutmann, MD, PhD, as a postdoctoral research fellow. Dr. Wright-Jin completed her MD and PhD training at Washington University in St. Louis School of Medicine under the mentorship of Robert Heuckeroth, MD, PhD, where she worked on the impact of […]

Amanda Costa has recently joined the research laboratory of the NF Center Director, David H. Gutmann, MD, PhD, as a postdoctoral research associate. She obtained her PhD with Helmut Kettenmann, PhD, at the Max Delbrück Center for Molecular Medicine and the Charité University of Medicine, Berlin, Germany, where she investigated the importance of microglia in […]

Children and adults with NF1 can develop a wide variety of clinical features, including brain and nerve tumors. While small animal models of NF1 have been successfully generated in flies and mice, none of these animals display the spectrum of clinical problems found in people with NF1. Spearheaded by Dr. Adrienne Watson of Recombinetics, Inc. […]

Jit Chatterjee, PhD recently joined the research laboratory of NF Center Director, David H. Gutmann, MD, PhD, as a postdoctoral research fellow. Dr. Jit completed his graduate training at Mangalore University in India, where he investigated radiation-induced brain cell dysfunction in mouse models. Over the next few years, Dr. Jit will be studying the role […]