Exceptional care, groundbreaking research
The Washington University NF Center is focused on accelerating the pace of scientific discovery and its application to the care of individuals with NF.
In 2018, as we celebrate 25 years of Neurofibromatosis research and clinical care at Washington University, Neurofibromatosis (NF) Center research and clinical members have continued to expand investigative initiatives aimed at developing personalized medical approaches for people affected with NF. We are grateful for the continued partnership with our families that make these high-risk, high-payoff ventures possible.
In a recent study, Dr. Angela Hirbe and her team analyzed βIII-spectrin expression in a series samples from patients cared for in the Washington University NF Center and the Siteman Cancer Center Sarcoma Program. While strong βIII-spectrin expression was detected in all high-grade MPNSTs, it was found in only half of the low-grade MPNSTs and in none of the benign tumors. These exciting results suggest that βIII-spectrin may be a sensitive marker for MPNSTs, which may aid in the diagnosis of these tumors.
On November 21, 2018, Brian and Amanda Walk and their daughters, Jordan and Bella, visited the Washington University NF Center to celebrate another successful fuNFest event. This year’s fuNFest raised over $18,000, which will fund laboratory research initiatives aimed at developing personalized medicine approaches for people with NF1. The Washington University NF Center extends its heartfelt gratitude to Amanda and Brain Walk, who worked tirelessly to plan this event.
Nov 27, 2018
In a recent study, Dr. Angela Hirbe and her team analyzed βIII-spectrin expression in a series samples from patients cared...
Nov 16, 2018
Corina Anastasaki, PhD, a senior Staff Scientist in the laboratory of David H. Gutmann, MD, PhD, was recently awarded one...
Oct 18, 2018
Children with Neurofibromatosis type 1 (NF1) are commonly shorter than typically developing children in the general population. While this short...