The Department of Defense Neurofibromatosis (NF) Research Program recently awarded Drs. Joshua Breunig (Cedars Sinai), David Gutmann (Washington University), and Yuan Pan (MD Anderson Cancer Center) a three-year grant to study NF1-associated brain tumors. The team will leverage a state-of-the-art genetic technology called Mosaic Analysis with Dual Recombinases (MDAR) to model brain tumors in NF1 and study the neuro-immune-cancer crosstalk. This project will provide insights into risk factors that drive brain tumor pathogenesis in NF1, and into therapeutic options for affected individuals.