Defining why people with NF1 have learning and memory deficits can be challenging in mice. For one, the human brain is far more complex than the mouse brain. In addition, it is not known whether brain nerve cells (neurons) from people with NF1 have the same abnormalities that have been reported in neurons from Nf1 […]
Month: April 2015
UPDATE: NF Clinical Trials – Spring 2015
Check out the NF Clinical Trials section of our website, which was recently updated to include current NF-related trials from clinicaltrials.gov. Some new studies that have been added are: NF1 Clinical Trials: Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis 1 CRAD001CUS232T Resiliency Training for Adolescent Neurofibromatosis Patients Via Videoconferencing With Skype NF2 Clinical Trials: Study of RAD001 […]
New Study Reveals the Complexity of RAS Signaling in the Brain
Recent work by Dr. R. Hugh Bender, a former PhD graduate student in Dr. David Gutmann’s laboratory, demonstrated that the consequence of RAS activation may be more complex than previously appreciated. One of the major functions of the Neurofibromatosis type 1 (NF1) protein, called neurofibromin, is to convert RAS from an active to an inactive […]
Courtney’s Corner: Improving Gross Motor Skills in Children with NF1
“Sports seem really hard for my child.” I often hear this comment from parents in the Washington University NF Center Clinical Program, and each time I feel frustrated that I don’t have a good recommendation to alleviate this concern. After observing the gross motor skills of over 100 children with NF1 in our clinic, I have […]