Dr. Jonathan Tiu received his medical degree from Tulane University in New Orleans and completed his Adult Neurology residency at New York University School of Medicine. Dr. Tiu is interested in how neurologic conditions impact everyday function, and divides his time between Neurofibromatosis, General Neurology and Neurorehabilitation at The Rehabilitation Institute of St. Louis. Dr. […]
Author: annawilson
NF Clinical Trials Consortium Identifies a New Therapy for Plexiform Neurofibromas
A recent study spearheaded by Dr. Michael Fisher at Children’s Hospital of Philadelphia and Dr. D. Wade Clapp at Indiana University found that cabozantinib as an effective therapy for NF1-associated plexiform neurofibromas. Using a preclinical mouse model of plexiform neurofibromas, this team showed cabozantinib was effective at reducing mouse tumors. Leveraging these exciting findings, they […]
Ji-Kang Chen Joins the Gutmann Laboratory
Ji-Kang Chen, MS recently joined the research laboratory of NF Center Director, David H. Gutmann, MD, PhD, as a Research Technician. He completed his master’s degree at Taiwan National Yang-Ming University, where he studied how hippocampal nerve cell (neuron) work in the brain. Bringing his expertise in neuron biology to the Gutmann laboratory, Ji-Kang is […]
First Human Models of NF1-Associated Neurofibromas Developed by NF Center Collaborative Team
The most common tumor in children and adults with NF1 is the neurofibroma, a peripheral nerve sheath tumor composed of Schwann-like cells. While mouse models of plexiform neurofibromas have been developed, Dr. Lu Le, Professor of Dermatology at the University of Texas-Southwestern joined forces with Drs. Corina Anastasaki and David Gutmann to develop a human […]
Gutmann Receives Neuro-oncology Scientific Award
David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and Vice Chair for Research affairs in the Department of Neurology at Washington University School of Medicine in St. Louis, is a recipient of the 2020 Neuro-oncology Scientific Award from the American Academy of Neurology. The award recognizes singular scientific achievement that has advanced […]
Celebrating the Life of Jeffrey Hanson
It is with a heavy heart that I write these parting words about Jeffrey Hanson. I am so grateful that I had the opportunity to get to know Jeff over these past few years. He was a remarkable young man who channeled the obstacles and challenges he faced with NF1 into amazingly beautiful artwork. He […]
Message from the Director
It has been a year like no other. As we all have learned to adjust to life during the COVID-19 pandemic, we have also had to grapple with inherent racial inequities in our country. It is not an understatement to say that these times have served as a flashpoint, prompting deep re-examination, extraordinary accommodations, and […]
NF Center Complementary Care Programs Go Virtual
At the Washington University NF Center, we believe in the value of extending medical care for our families beyond the walls of the clinic. As such, we have pioneered several successful therapy programs, including Beat NF, Club NF and Teen NF. The COVID-19 pandemic has challenged our team to find creative ways to offer these […]
Andrea Goldstein Joins the Gutmann Laboratory
Andrea Goldstein, BS recently joined the research laboratory of NF Center director, David H. Gutmann, MD, PhD, as a Research Technician. She completed medical school at the University of MIssouri in Columbia, and is currently applying to residency programs in Obstetrics/Gynecology. Her prior laboratory experience includes work in the laboratory of Michelle Monje MD, PhD […]
Patient Spotlight: Jeffrey Hanson
In viewing the artistic work of Jeffrey Hanson, one may be drawn to the vibrant colors, to the emphasis on texture, or maybe to the accomplishments of the artist himself. Diagnosed with NF1 in childhood, and enduring chemotherapy and radiation for an optic glioma tumor at 12, Jeff Hanson has surely faced his obstacles. He […]
NF Center Trainee Publishes Groundbreaking Study on the Origins of NF1 Optic Gliomas
Dr. Nicole Brossier, Instructor in the Division of Pediatric Hematology and Oncology at St. Louis Children’s Hospital, recently reported that numerous factors explain why children with NF1 develop optic gliomas. In her study, Dr. Brossier, who is a pediatric neuro-oncologist specializing in the care of children with NF1-associated brain tumors, showed that the cells which […]
Alexander Chen awarded Training Grant from the Center of Regenerative Medicine
Alexander Chen, PhD, a postdoctoral fellow in the Gutmann Laboratory, was recently awarded a “Training in Regenerative Medicine” training grant (T32) from the National Institute of Biomedical Imaging and Bioengineering. This program aims to develop highly-trained individuals by providing a unique, multidisciplinary experience for postdoctoral fellows. Dr. Chen is honored and privileged to be one […]
JSL Awarded an Arts and Healing Initiative Grant
Jazz St. Louis is pleased to announce that the Beat NF program, a jazz-music motor therapy program, has been awarded an Arts and Healing Initiative Grant from the Arts and Education Council (A&E). This grant is part of a new effort developed with the Missouri Foundation for Health to increase the capacity for the arts […]
Kyra Rosen Joins the NF Center
The NF Center recently welcomed a new undergraduate student, Kyra Rosen, to the team. Kyra studies philosophy and art history at Washington University in St. Louis, and is pursuing a career in medicine and public health. In the NF Center, she will be researching access to healthcare services for those with NF.
International NF Collaborative Research Reveals Brain Sex Differences
As part of a Berlin Institute of Health Einstein Fellowship, investigators at the Max Delbrück Center in Berlin worked with NF Center Director, David H. Gutmann, to discover sex differences in microglia function. In this study, researchers in the laboratory of Professor Helmut Kettenmann found that mouse brain cells, called microglia, react differently to Neurofibromatosis […]
NF Center 2020 Annual Report Published
Check out the NF Center 2020 Annual Report (pdf) to read a message from the Director, learn more about groundbreaking research in the Gutmann Laboratory, and read about a new therapy treatment for children with NF1. Additionally, learn about: Support beyond the clinic Research grants awarded to the NF Center team If you haven’t already […]
Gutmann Receives Award from the American Neurological Association
Honored for work on role of immune system in brain tumors David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and Vice Chair for Research Affairs in the Department of Neurology at Washington University School of Medicine in St. Louis, has received the George W. Jacoby Award from the American Neurological Association for […]
Beat NF Highlighted During the Jazz St. Louis 25th Anniversary Celebration
On October 2, 2020, Jazz St. Louis celebrated their 25th Anniversary with a virtual party broadcast live on YouTube. The event featured a preshow performance by JazzU students, performances and birthday messages from jazz artists across the country, and an after party concert with Denise Thimes. The event also included stories from patrons, partners, and […]
Alexander Chen joins the Gutmann Laboratory
Alexander S. Chen, PhD recently joined the research laboratory of NF Center Director, David H. Gutmann, MD, PhD, as a postdoctoral research scientist. Dr. Chen completed his PhD training in Cancer Biology at Emory University in Atlanta, Georgia. Under the mentorship of Renee D. Read, PhD, Dr. Chen investigated how the novel protein kinases RIOK2 […]
Gutmann Awarded Three-Year Drug Discovery Grant
David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and Vice Chair for Research Affairs in the Department of Neurology at the Washington University School of Medicine, was awarded a three-year grant from the Pediatric Brain Tumor Foundation. The Pediatric Brain Tumor Foundation award will support Dr. Gutmann’s research on pediatric low-grade […]