Researchers Discover New Mechanism for Learning Problems in NF1

Learning deficits are a major clinical problem affecting children with neurofibromatosis type 1 (NF1). Using novel genetically-engineered mouse strains, Dr. Ype Elgersma, from the Erasmus Medical Center in the Netherlands, determined how brain cells control learning and memory retrieval. Dr. Elgersma, working with colleagues in the Washington University NF Center, demonstrated that Nf1 mouse strains […]

Dr. Angela Hirbe Receives Grant from St. Louis Men’s Group Against Cancer

Angela Hirbe,  MD, PhD, a postdoctoral fellow in the laboratory of David H. Gutmann was awarded a grant from the St. Louis Men’s Group Against Cancer to further her work on malignant peripheral nerve sheath tumors (MPNSTs). MPNSTs are highly aggressive cancers that arise in adults with NF1. Dr. Hirbe is focused on finding new […]

Researchers Use Whole Genome Sequencing to Identify Genes Involved in Malignant Peripheral Nerve Sheath Tumor Formation in NF1

Malignant peripheral never sheath tumors (MPNSTs) are extremely aggressive soft tissue sarcomas that occur more frequently in people with the Neurofibromatosis 1 (NF1) tumor predisposition syndrome.  These cancers often arise from benign plexiform neurofibromas. Over the last several years, since completion of the sequencing of the human genome, whole genome sequencing techniques have become an […]

NF1 Patient Elana Loftspring: Making a Difference

This isn’t the first time we are reporting about the hard work this extraordinary young woman is doing to make a difference in the lives of individuals with NF, and I doubt it will be the last. Several weeks ago, members of the Washington University NF Center had the pleasure of meeting with Elana and […]

Nicole’s Nook: Third Party Keyboard Use Finally Introduced in iOS8!

One of the most significant new features of iOS8 is the option to download and use third party keyboards. Essentially, it allows for what many of us have been eagerly awaiting, the ability to use an app within an app. You can now replace the standard built-in keyboard with other custom and specialized keyboards available […]