The Washington University NF Center in collaboration with Dr. Mohamed Abdelbaki in Pediatric Neuro-Oncology has initiated a virtual International Tumor Board to discuss the management of children and adults with NF. For these quarterly meetings, we leverage the expertise of dedicated specialists in the NF Center, including those in Adult and Pediatric Neurosurgery, Adult and […]
Month: October 2021
PATIENT SPOTLIGHT: CARTER
Carter Hoss is a goofy, caring, and fun-loving sixth grader. He has also raised over $1500 to benefit NF Midwest through participation in the organization’s annual Walk 4 NF event. Both aspects of Carter stem from his drive to constantly improve himself and the world around him, always on a mission to help however he […]
New Autism Gene Discovered Using Human Mini-Brains
Neurodevelopmental disorders are often caused by losses of large pieces of chromosomes containing many genes. This is also true for a subset of individuals with Neurofibromatosis type 1 (NF1) who have severe developmental delays and intellectual disabilities. These NF1 patients often harbor a large deletion involving the NF1 gene on chromosome 17q11.2, termed a total […]
Brain tumors caused by normal neuron activity in mice predisposed to such tumors
Light triggers formation, feeds growth of optic nerve tumors Seeing, hearing, thinking, daydreaming — doing anything at all, in fact — activates neurons in the brain. But for people predisposed to developing brain tumors, the ordinary buzzing of their brains could be a problem. A study by researchers at Washington University School of Medicine in […]
New Study Identifies Immune Cell Target for Blocking Tumor Growth
Previous studies from the laboratory of NF Center director, David H. Gutmann, MD, PhD, have shown that immune system-like cells, called microglia, are important non-cancerous regulators of NF1 optic glioma formation and growth. Using a combination of RNA sequencing, genetically engineered mouse strains, and human tumor specimens, Amanda de Andrade Costa and colleagues discovered that […]